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. 2014 Sep 27;12:273. doi: 10.1186/s12967-014-0273-3

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© Jiang et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Expression of galectin-3 mRNA and protein in human primary HCC cell lines and tissues as evaluated by real-time quantitative PCR and Western blotting. (A) The protein transcript levels of galectin-3 in the Hep3B, Huh7, HepG2, and Bel7402 HCC cells were higher than in the normal liver cell line LO2. (B) The relative mRNA expression of galectin-3 was higher in 44 HCC tumor tissues than in adjacent non-tumor tissues (p = 0.039). (C) Galectin-3 protein expression was increased in tumor tissues compared with adjacent non-tumorous tissues (p = 0.002).