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. 2014 Sep 27;12:273. doi: 10.1186/s12967-014-0273-3

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© Jiang et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Decreased galectin-3 and CD34 expression in surgical specimens of primary hepatocellular carcinoma (n = 165) detected by immunohistochemistry. (A1-4) Immunohistochemical staining for galectin-3 expression in human hepatocellular carcinoma. (A1) Adjacent non-tumorous tissues. (A2) Poorly differentiated hepatocellular carcinoma. (A3) Moderately differentiated hepatocellular carcinoma. (A4) Well-differentiated hepatocellular carcinoma. (A5-6) Immunohistochemical staining for CD34 antigen in human hepatocellular carcinoma. Original magnification for A1–A6, ×200. (B) Based on the results of immunohistochemical staining, the HCC patients (n = 165) were divided into high galectin-3 expression (n = 135) and low galectin-3 expression (n = 30) after resection. Log-rank test revealed that patients in the low-expression group exhibited significantly better survival than those in the high-expression group (P < 0.01).