Table 2.

Summary of technical performance for 3 biomarkers assays

	C-Col10 (pg/ml)	hsCRP (μg/ml)	C2M (pg/ml)
Assay specifications
Slope of standard curve	1.23	n. a.	0.96
IC50, pg/ml	363	n. a.	440
Intra-assay CV%	4.19	n. a.	3.95
Inter-assay CV%	13.18	<5	9.88
Lower limit of detection	24	n. a.	n. a.
Quantifiable range	40-7300	0.2-10	30-1700

C-Col10: C-terminus of ColX assay; C2M: MMP-derived collagen type II fragment assay; hsCRP: high sensitive CRP assay. n.a.: not available.