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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Alcohol Clin Exp Res. 2014 Sep;38(9):2414–2426. doi: 10.1111/acer.12525

Fig. 10.

Fig. 10

Activation of Epac enhances endothelial barrier function, but does not block alcohol-induced decreases in barrier dysfunction. (A and B) Time courses showing changes in TER of HUVEC pretreated with 100 µM 8-CPT or vehicle (water) for 30 minutes followed by addition 50 or 100 mM alcohol. (C) Maximum change in HUVEC TER following addition of alcohol, compared to the time point at which alcohol was added. N=8 for all groups.