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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Alcohol Clin Exp Res. 2014 Sep;38(9):2414–2426. doi: 10.1111/acer.12525

Fig. 11.

Fig. 11

Activation of Epac accelerates recovery during alcohol-induced barrier dysfunction. (A and B) Time course of changes in HUVEC monolayer TER in response to 50 or 100 mM alcohol, followed by addition of 100 µM 8-CPT 5 or 10 min later, or vehicle (water) 5 min later. (C) Mean recovery time for HUVEC, i.e. time to return to baseline TER, starting from the time point at which alcohol was added. **P<0.01 versus alcohol/vehicle group. N=12 for all groups.