Table 3. Pairwise interactions. Residue – base contacts (< 5Å distance) observed between 40S ribosomal proteins and the HCV IRES RNA, are listed.

Pairwise interactions: S5	Pairwise interactions: S25
ALA-131 CYT-83 ALA-161 ADE-72 ALA-161 GUA-71 ALA-161 GUA-94 ARG-127 GUA-87 ARG-127 GUA-88 ARG-136 GUA-87 ARG-136 GUA-88 ARG-164 GUA-94 ARG-164 URI-91 ARG-198 ADE-74 ASN-165 ADE-70 ASN-165 GUA-71 ASN-165 GUA-94 ASN-179 ADE-70 ASN-179 GUA-98 ASN-186 ADE-70 ASN-186 ADE-98 ASN-186 GUA-71 ASN-186 GUA-98 ASN-203 GUA-87 ASN-203 URI-86 ASP-175 ADE-70 ASP-175 GUA-71 CYS-172 GUA-71 GLU-171 ADE-70 GLU-195 ADE-73 GLU-195 ADE-74 GLY-132 CYT-83 GLY-132 CYT-84 ILE-178 ADE-99 LEU-103 GUA-100 LYS-167 ADE-70 LYS-167 GUA-70 LYS-182 ADE-99 LYS-182 GUA-100 LYS-191 ADE-72 LYS-191 ADE-73 LYS-192 GUA-90 SER-184 ADE-99 SER-184 GUA-98 SER-185 ADE-72 SER-187 ADE-72 SER-187 GUA-71 THR-133 CYT-84 THR-133 URI-86 TYR-188 ADE-72 TYR-188 GUA-71 VAL-134 ADE-85 VAL-134 CYT-84 VAL-134 GUA-87 VAL-134 URI-86 VAL-199 GUA-87	GLY-115 GUA-68 GLY-116 GUA-68 LEU-67 CYT-69 LEU-67 GUA-68 LYS-114 ADE-66 LYS-114 CYT-67 LYS-114 GUA-68 LYS-66 CYT-69 LYS-66 GUA-68 TYR-65 CYT-69
	Pairwise interactions: S26
	ARG-51 URI-329 TYR-62 URI-306
	Pairwise interactions: S3a
	GLN-202 GUA-299 GLN-202 GUA-300 LYS-195 GUA-301 LYS-195 URI-302 LYS-199 GUA-299 LYS-199 GUA-300 LYS-199 GUA-301
	Pairwise interactions: S27
	CYS-40 URI-234 ILE-43 GUA-235 LYS-36 CYT-236 LYS-36 GUA-235 LYS-42 GUA-235 LYS-42 URI-234 SER-78 CYT-236 TYR-41 GUA-233 TYR-41 GUA-235 TYR-41 URI-234 ARG-80 CYT-151 ARG-81 GUA-150