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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Contraception. 2014 Jun 27;90(5):550–556. doi: 10.1016/j.contraception.2014.06.033

Figure 2.

Figure 2

LNG and EE concentrations at baseline while using 20mcg EE/100mcg LNG (closed squares/circles) and following randomization (open squares/circles). Panel A: LNG; Higher dose cyclic study group; Panel B LNG; Continuous OC study group; Panel C: EE; Higher dose cyclic study group; Panel D: EE; Continuous OC study group. While the increased dose results in higher concentrations, the time to reach steady state is not affected. In contrast, the continuous dosing eliminates the drop in drug levels associated with the HFI.