Figure 6. Evaluating cytotoxicty of exosome-based miRNA-155 inhibitor delivery and transfection reagants.
After 36 hours of co-culture, miRNA-155 loaded exosomes showed minimal toxicity, while miRNA-155 inhibitor + FuGENE HD, and miRNA-155 inhibitor + HiPerFect showed significant cytotoxicity (p<0.05). Results are representative of three independent experiments. (*indicates p < 0.05 versus non treated RAW 264.7 macrophages).