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. 2014 Sep 18;9:129. doi: 10.1186/s13023-014-0129-1

Table 4.

Contingency table and statistical analysis of splenomegaly data

Group Pre-post McNemar test p-value Positive outcomes
Y-Y Y-N N-Y N-N Proportion CI (95%)
A 0 1 3 5 0.63 0.67 (0.299, 0.925)
B 2 2 0 2 0.50 0.67 (0.223, 0.957)
C 2 3 0 2 0.25 0.71 (0.290, 0.963)
A + B 2 3 3 7 1.00 0.67 (0.384, 0.882)
A + B + C 4 6 3 9 0.51 0.68 (0.451, 0.861)

The category “Positive Outcomes” includes both YES-NO (Y-N: improvement) and NO-NO (N-N: stabilization) cases. Confidence intervals, calculated by the Clopper and Pearson method and the p-value of McNemar test are reported. Group A: n = 9, group B: n = 6, group C: n = 7.