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. Author manuscript; available in PMC: 2014 Sep 30.
Published in final edited form as: Curr Top Membr. 2014;73:357–382. doi: 10.1016/B978-0-12-800223-0.00010-4

Figure 10.3.

Figure 10.3

The function of G6PT. (A) Uptake of G6P into hepatic microsomes of wild-type mice (○), GSD-Ia mice (•), or GSD-Ia mice at day 14 post Ad-G6Pase-α infusion (△). (B) The cell-based microsomal G6P uptake activity. Uptake of G6P into microsomes prepared from COS-1 cells transfected with cDNA encoding G6PT alone (△), G6Pase-α alone (□), or G6PT and G6Pase-α (○). (C) The antiporter activity of G6PT. G6P uptake (left) and Pi uptake (right) were determined in proteoliposomes expressing G6PT preloaded with 50 mM Pi (○) or with MOPS buffer (•). Data are presented as the mean SEM.