Table 2.

Group differences in the novelty and familiarity condition

			Familiarity condition				Novelty condition
				Talairach coordinates				Talairach coordinates
Contrast	Lobe	Region	z	x	y	z	z	x	y	z
HC > RBD	Anterior	Left culmen	4.10	−24	−30	−24	4.10	−36	−42	−18
	Midbrain	Left subthalamic nucleus	3.50	−10	−18	−2
	Occipital	Left cuneus (BA18)					3.42	−18	−92	12
		Right fusiform gyrus (BA18)					2.69	30	−88	−14
		Right fusiform gyrus (BA19)	2.60	34	−70	−10
		Right inferior occipital gyrus (BA17)	3.44	14	−92	−6	2.96	14	−92	−6
		Left lingual gyrus (BA17)	4.15	−20	−90	0	3.23	−20	−88	0
		Right lingual gyrus (BA17)	3.30	18	−86	−2	2.60	18	−86	−2
		Left lingual gyrus (BA18)	3.69	−12	−72	−6	3.34	−12	−86	−8
		Right lingual gyrus (BA18)	3.21	34	−68	−4	2.45	16	−80	−6
		Left middle occipital gyrus (BA18)	4.15	−18	−98	8	3.75	−18	−96	6
		Right middle occipital gyrus (BA18)	3.53	24	−84	0	3.29	24	−82	0
	Limbic	Left parahippocampal gyrus (BA36)					3.81	−34	−28	−22
		Right posterior cingulate (BA31)					2.55	28	−60	22
	Parietal	Right inferior parietal lobule (BA40)					2.34	38	−52	42
		Right precuneus (BA7)	3.09	16	−60	44	3.65	30	−48	40
		Right superior parietal lobule (BA7)	3.44	34	−58	54
	Posterior	Left declive	3.90	−36	−60	−14
		Right declive	3.32	32	−80	−16
	Sub-lobar	Left lentiform nucleus (putamen)	3.66	−16	2	12
		Left thalamus	3.83	−18	−30	0
	Temporal	Left fusiform gyrus (BA37)	3.74	−36	−52	−12	3.38	−42	−40	−14
		Right fusiform gyrus (BA37)	2.92	40	−62	−8
		Left fusiform gyrus (BA20)	3.53	−38	−34	−18
		Left inferior temporal gyrus (BA20)	3.50	−60	−48	−14
		Left inferior temporal gyrus (BA37)	3.16	−64	−50	−8
		Left middle temporal gyrus (BA21)	3.33	−66	−32	−2
RBD > HC	Frontal	Right inferior frontal gyrus (BA9)					2.76	54	6	32
		Left medial frontal gyrus (BA9)					2.88	−4	48	16
		Left medial frontal gyrus (BA11)					3.77	−6	34	−12
		Left medial frontal gyrus (BA10)					2.54	−6	48	−4
		Right middle frontal gyrus (BA6)					2.82	48	2	42
		Right precentral gyrus (BA6)	3.69	54	2	36	3.12	54	−4	32
	Limbic	Left anterior cingulate (BA24)					3.55	−2	32	10
		Left anterior cingulate (BA32)					3.00	−10	38	12

Maps, created through spatial mixture models, were thresholded at z ≥ 2.3 and p < 0.0001. Highlighted rows indicate differences in activation that occurred during both conditions. RBD = remitted bipolar disorder patients; HC = healthy controls; BA = Brodmann area.