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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Am J Reprod Immunol. 2014 May 23;72(4):403–412. doi: 10.1111/aji.12273

Figure 2.

Figure 2

Protein-protein interaction network of the identified candidate galectin-3 binding ligands in seminal plasma. A protein-protein interaction map was generated using data obtained from the HPRD, BioGRID, IntAct database, and NCI/Nature Pathway Interaction Database. Large nodes indicate the galectin-3 affinity purified proteins identified in this study. Small nodes represent proteins that interact with the candidate galectin-3 binding ligands based on the database search. Connecting lines indicate protein interactions. Each protein is shown by its gene symbol or Entrez identification number. Angiotensin-converting enzyme (ACE), attractin (ATRN), CD13 (ANPEP), clusterin (CLU), galectin-3 (LGALS3), mucin 6 (MUC6), prostatic acid phosphatase (PAP), prostate specific antigen (NPEPPS), prostaglandin-H2 D-isomerase (PTGDS), and zinc α2-glycoprotein (AZGP1).