Table 4.

DAVID enrichment analysis

Term	P-value	Adjusted1 P-value
25(OH)D-associated genes
Defense response to bacterium	<0.001	0.024
Defense response	<0.001	0.026
Response to bacterium	<0.001	0.130
Serine-type endopeptidase activity	<0.001	0.022
Serine-type peptidase activity	<0.001	0.022
IFNB-1b-associated genes
Defense response	<0.001	<0.001
Response to wounding	<0.001	<0.001
Inflammatory response	<0.001	<0.001
Regulation of apoptosis	<0.001	0.004
Regulation of programmed cell death	<0.001	0.005
GEL-associated genes
Defense response	<0.001	0.001
Inflammatory response	<0.001	0.095
MHC class I protein complex	<0.001	0.100
Antigen processing and presentation	<0.001	0.140
Regulation of I-kappaB kinase/NF-kappaB cascade	<0.001	0.140

DAVID, Database for Annotation, Visualization and Integrated Discovery; 25(OH)D, 25-hydroxyvitamin D; IFNB-1b, interferon beta-1b; GEL, gadolinium-enhancing lesions; MHC, major histocompatibility complex.

¹FDR corrected using the Benjamini and Hochberg (BH) adjustment.20