Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Sep 18;14:675. doi: 10.1186/1471-2407-14-675

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© McGoldrick et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

LNCaP and COS-7-OPH show increased oxidative stress and apoptosis after treatment with S-NPAA. A) RWPE-1, LNCaP, COS-7, and COS-7-OPH cell cultures were incubated with 25 μM S-NPAA for 6 hours. Protein carbonyl levels were measured in cellular lysates as described in the Methods Section. B) RWPE-1, LNCaP, DU145, PC3, COS-7, and COS-7-OPH cell cultures were incubated with 25 μM NPAA or 5 μM staurosporine (STS) as a positive control for 6 hours and caspase-3 activities in cellular lysates were measured as described in the Methods Section; *indicates that the S-NPAA treatment was significantly different from control (vehicle) at p < 0.05. C) RWPE-1 and LNCaP lysates were also examined for DNA fragmentation under the same conditions.