Table 5.
Multivariate Logistic Regression Model*
Variable | Risk of Bleeding |
P Value (Univariate Analysis) |
P Value (Multivariate Analysis) |
Risk Ratio |
---|---|---|---|---|
Anemia, g/dL† | Higher | .007 | NS | |
Thrombocytopenia, ×109/L | Higher | .001 | .02 | 1.002 |
PB blast %, higher | Higher | .049 | NS | |
BM blast %, higher | Higher | .002 | NS | |
Longer CML duration | Higher | .049 | NS | |
CML phase: AP/BP (vs CP) | Higher | .002 | .03 | 1.69 |
Prior IFN-α (yes) | Higher | .08 | NS |
NS indicates not significant; PB, peripheral blood; BM, bone marrow; CML, chronic myelogenous leukemia; AP, accelerated phase; BP, blast phase; CP, chronic phase; IFN-α, interferon-α.
Estimation of the association between disease and patient characteristics and the development of bleeding, considering other covariates in the model.
Anemia denotes a hemoglobin level <10 g/dL.