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. 2014 Sep 29;9(9):e108489. doi: 10.1371/journal.pone.0108489

Table 1. Distribution of 24 narcolepsy cases according to exposure status and patients’ characteristics.

Patient’s characteristics Mean ± SD/median/range All cases (n = 24) Not vaccinated or vaccinated after disease onset (n = 16) Vaccinated before disease onset (n = 8) p value*
Age (years) 24.0±14.3 26.1±13.1 19.9±16.6 0.20
18.1 28.2 13.7
6–55 8–55 6–50
Age group
<20 years of age 13 (54%) 7 (44%) 6 (75%) 0.21
≥20 years of age 11 (46%) 9 (56%) 2 (25%)
Male proportion 12 (50%) 10 (62.5%) 2 (25%) 0.19
Cases with cataplexy 16 (67%) 10 (63%) 6 (75%) 0.67
Cases with hypnagogic hallucinations 14/23 (61%) 9 (56%) 5/7 (71%) 0.66
Cases with sleep paralysis 10 (42%) 7 (44%) 3 (38%) 1.00
Cases with all signs and symptoms 5 (21%) 3 (19%) 2 (25%) 1.00
Diagnostic certainty
Brighton level 1 4 (17%) 2 (12.5%) 2 (25%) 0.73
Brighton level 2 12 (50%) 8 (50%) 4 (50%)
Brighton level 3 8 (33%) 6 (38%) 2 (25%)
HLA DQB1*0602 positive 19/24 (79%) 12/16 (75%) 7/8 (88%) 0.63
Interval between onset first sleep 53.3±93.1 72.3±116.9 24.8±27.5 1.00
symptoms and onset of cataplexy (days) 21 0 23
0–330 0–330 0–91
Interval between disease onset and first 149.1±187.8 190.9±218.9 65.5±35.7 0.42
medical visit (days) 70.5 77.5 52.5
3–799 3–799 32–124
Interval between disease onset and 427.8±244.52 482.1±239.3 319.3±231.4 0.15
confirmatory laboratory investigations 414 422 246
(days) 79–903 170–903 79–756

*Fisher exact test for proportions and Wilcoxon rank test for medians.