Table 2.
Cognitive correlates of MoCA-based PD-MCI classification in PD subjects with normal range MMSE scores.
| PD without MCI (n=29) | PD-MCI (n=18) | Statistical significance | |
|---|---|---|---|
| Global composite z-score | −0.02±0.67 | −0.62±0.70 | t=2.91, P=0.0056* |
| Verbal learning z-score | −0.09±1.07 | −0.92±1.14 | t=2.53, P=0.015 |
| CVLT Immediate learning | 9.7±1.9 | 8.0 ±2.3 | t=2.58, P=0.013 |
| CVLT short-term memory | 10.7±3.5 | 8.3 ±3.1 | t=2.32, P=0.025 |
| CVLT long-term memory | 11.1±3.2 | 8.9 ±3.5 | t=2.17, P=0.035 |
| Executive functions z-score | −0.02±0.79 | −0.81±0.86 | t=3.18, P=0.0027* |
| DKEFS card sorting test 1 | 19.1±4.1 | 15.8±5.9 | t=2.22, P=0.032 |
| DKEFS card sorting test 2 | 20.7±5.0 | 16.1±6.1 | t=2.80, P=0.008 |
| DKEFS verbal fluency letter test (F-A-S) | 46.9±13.7 | 36.4 ±11.4 | t=2.71, P=0.0096 |
| Picture Arrangement test | 14.7±5.2 | 11.4±5.4 | t=2.06, P=0.045 |
| Stroop Color Word Interference test 3 vs. 1–2 | 64.2 ±21.9s | 85.9±s44.5 | tapprox=1.88, P=0.074 |
| Stroop Color Word Interference test 4 vs. 1–2 | 77.5 ±30.8s | 99.6±51.8s | tapprox=1.60, P=0.122 |
| Visuospatial function z-score | 0.32±0.76 | −0.18±1.06 | t=1.93, P=0.060 |
| Benton Judgment of Line Orientation | 26.0±3.3 | 23.8±4.6 | t=1.93, P=0.060 |
| Attention z-score | −0.28±0.80 | −0.84±1.10 | t=1.98, P=0.054 |
| Stroop test 1 | 52.2±9.7s | 59.0±14.8s | t=1.75, P=0.091 |
| Stroop test 2 | 68.6 ±11.2s | 76.7±15.9s | t=2.03, P=0.048 |
Mean values with standard deviation are given. Raw test scores on the domain-specific cognitive sub-tests in italics. Stroop test scores are presented in seconds (s). Abbreviations: CVLT=California Verbal Learning Test; DKEFS=Delis-Kaplan Executive Function System; tapprox=Satterthwaite’s t-test approximation.
*
Significant variable after Holm-Bonferroni correction applied for the domain-specific Z-scores.