Table 1.
Clubfoot Cases |
Controls | |
---|---|---|
(n=622) | (n=2002) | |
|
||
No. (%) | No. (%) | |
Maternal race/ethnicity | ||
White non-Hispanic | 450 (72) | 1307 (65) |
Black non-Hispanic | 80 (13) | 334 (17) |
Hispanic | 70 (11) | 241 (12) |
Other/Unknown | 22 (4) | 120 (6) |
Maternal age at conception (years) | ||
<25 | 190 (31) | 600 (30) |
25–29 | 183 (29) | 558 (28) |
30–34 | 153 (25) | 516 (26) |
≥35 | 96 (15) | 328 (16) |
Maternal education (years) | ||
< 12 | 77 (12) | 278 (14) |
12 | 158 (25) | 448 (22) |
> 12 | 387 (62) | 1276 (64) |
Parity | ||
Nulliparous | 304 (49) | 802 (40) |
Multiparous | 318 (51) | 1200 (60) |
Maternal cigarette smoking in lunar months 2 or 3 | ||
Smoked | 164 (26) | 353 (18) |
Did not smoke | 449 (72) | 1632 (82) |
Missing data | 9 (1) | 17 (1) |
Maternal alcohol use in lunar months 2 or 3 | ||
Used alcohol | 55 (9) | 122 (6) |
Did not use alcohol | 536 (86) | 1798 (90) |
Missing data | 31 (5) | 82 (4) |
Maternal body mass index (kg/m2) | ||
< 18.5 | 21 (3) | 85 (4) |
18.5– < 24.9 | 289 (46) | 1062 (53) |
25– <30 | 168 (27) | 445 (22) |
≥ 29.9 | 127 (20) | 351 (18) |
Missing data | 17 (3) | 59 (3) |
Infant sex | ||
Male | 452 (73) | 993 (50) |
Female | 170 (27) | 1009 (50) |
First degree family history of clubfoot | ||
None | 551 (89) | 1987 (99) |
Yes | 71 (11) | 15 (1) |
Study center | ||
North Carolina | 254 (41) | 990 (49) |
New York | 199 (32) | 560 (28) |
Massachusetts | 169 (27) | 452 (23) |