Figure 6.
(a) Representative PET and three-dimensional (3D) PET reconstruction images of 64Cu-doped AuNCs on U87MG glioblastoma bearing mice. Images were acquired at 1, 3, 8, 18 and 24 h. (b) Tumor and muscle uptake of 64Cu-doped AuNCs, measured by VOIs. Date were average decay-corrected to the time of injection, presented as %ID/g; (c) Tumor/muscle (T/NT) ratio at different time point; Tumor was marked by dashed circles or white arrow; n=4.