Table 4.

Item endorsement frequencies for the six-class LCA solution for all 27 symptoms independently assessed for the lifetime worst depressive episode^a

Item description	Severe typical	Moderate typical	Low suicidal high guilt	Non-suicidal low guilt	Atypical	Mild	F/χ 2	Cramér’s V/η2
Class counts	2376	1169	1020	656	439	348
Class proportions (%)	39.5	19.5	17.0	10.9	7.3	5.8
Depressed mood	1.00	1.00	1.00	0.99	1.00	0.94		0.22
Anhedonia	1.00	0.99	1.00	0.97	1.00	0.92		0.19
Loss of appetite	0.97	0.81	0.89	0.76	0.52	0.55		0.40
Loss of weight	0.75	0.52	0.62	0.54	0.27	0.34		0.32
Increase of appetite	0.04	0.02	0.01	0.07	0.77	0.08		0.73
Increase of weight	0.01	0.00	0.01	0.05	0.65	0.07		0.73
Insomnia	0.97	0.90	0.96	0.89	0.85	0.80		0.21
Hypersomnia	0.13	0.12	0.08	0.12	0.38	0.11		0.22
Psychomotor retardation	0.90	0.65	0.82	0.66	0.79	0.25		0.40
Psychomotor agitation	0.86	0.62	0.77	0.60	0.77	0.34		0.34
Fatigue	0.99	0.89	0.96	0.93	0.91	0.73		0.29
Worthless	0.98	0.83	0.85	0.35	0.92	0.41		0.58
Guilt	0.88	0.66	0.80	0.41	0.82	0.46		0.39
Trouble concentrating	0.99	0.85	0.97	0.90	0.97	0.47		0.49
Slower/mixed-up thoughts	0.99	0.81	0.94	0.87	0.97	0.34		0.54
Trouble making decision	0.98	0.72	0.93	0.69	0.89	0.28		0.53
Thoughts of death	0.99	0.96	0.29	0.10	0.80	0.38		0.78
Thoughts of suicide	0.94	0.87	0.05	0.03	0.69	0.23		0.83
Lack of mood reactivity	0.97	0.85	0.84	0.76	0.88	0.54		0.32
Distinct quality to mood	0.96	0.93	0.93	0.90	0.91	0.85		0.12
Worse mood in the morning	0.70	0.51	0.68	0.57	0.68	0.42		0.20
Loss of sexual drive	0.96	0.84	0.92	0.87	0.88	0.63		0.27
Irritability/anger	0.84	0.63	0.77	0.63	0.85	0.66		0.24
Hopeless	0.99	0.87	0.81	0.22	0.89	0.45		0.65
Cry a lot	0.78	0.62	0.68	0.45	0.72	0.57		0.25
Helpless	0.99	0.86	0.98	0.61	0.95	0.67		0.46
Nervous, jittery or anxious	0.97	0.81	0.95	0.80	0.93	0.70		0.30
Continuous validators							F	η 2
Age	45.15 (0.18)	44.72 (0.26)	43.36 (0.28)	44.84 (0.34)	41.90 (0.41)	44.08 (0.48)	4.25	0.00
Body mass index	22.83 (0.07)	22.72 (0.10)	22.3 (0.10)	22.6 (0.13)	23.71 (0.18)	22.67 (0.19)	37.79**	0.01
Age of onset	35.18 (0.20)	34.91 (0.29)	34.09 (0.30)	36.32 (0.37)	31.96 (0.46)	35.5 (0.54)	1.65	0.00
Duration of the worst  episode	47.27 (1.82)	47.04 (2.59)	48.92 (3.10)	36.35 (2.37)	72.13 (5.98)	42.4 (4.80)	8.59*	0.00
Neuroticism	14.21 (0.12)	11.62 (0.17)	12.89 (0.18)	9.28 (0.20)	15.08 (0.25)	9.29 (0.29)	206.21**	0.03
Number of episodes	5.09 (0.16)	4.03 (0.18)	4.46 (0.22)	3.87 (0.22)	5.49 (0.39)	3.64 (0.27)	16.39**	0.00
Stressful life events	1.67 (0.04)	1.52 (0.05)	1.40 (0.05)	1.20 (0.06)	2.09 (0.10)	1.45 (0.08)	61.81**	0.01
Binary external validators (%)							χ 2	Cramér’s V
Childhood sexual abuse	9.3 (0.6)	11 (0.9)	11 (1.0)	8.1 (1.1)	15.9 (1.8)	8.8 (1.5)	22.4**	0.06
Dysthymia	11.1 (0.6)	9.8 (0.9)	7.9 (0.8)	5.8 (0.9)	15.6 (1.7)	7.5 (1.4)	38.97**	0.08
Family history	28.7 (0.9)	24.7 (1.3)	26.7 (1.4)	22.2 (1.7)	32.5 (2.3)	22.4 (2.3)	23.73**	0.06
Generalized anxiety  disorder	33.1 (1.0)	19.8 (1.2)	22.5 (1.3)	15.1 (1.4)	33.7 (2.3)	12.0 (1.8)	180.81**	0.17
Panic disorder	9.0 (0.6)	4.6 (0.6)	7.1 (0.8)	3.7 (0.7)	7.6 (1.3)	2.3 (0.8)	48.01**	0.09
Phobia	46.5 (1.0)	32.4 (1.4)	36.8 (1.5)	31.8 (1.8)	48.3 (2.4)	28.1 (2.4)	124.28**	0.15

LCA, Latent class analysis.

^aFor binary external validators, frequencies (and standard errors) are reported for each class, Cramér’s V as the effect size and χ² and p values; for quantitative external validators, means (and standard errors) are reported for each class, along with η² as the effect size, and F and p values for the ANOVA.

^*p<0.005,

^**p<0.0005, otherwise p ≥ 0.01.