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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Metab Brain Dis. 2013 Oct 18;29(4):983–989. doi: 10.1007/s11011-013-9439-6

Table 2.

Reported values for the inhibition of glutamine synthetases by MSO

Source Ki MSO (mM) Km Glu (mM) Km ATP (mM) References
Human 1.19a 1.67a, 3.00b & 3.50b 1.80b & 2.8b a This study & bListrom et al. (1997)
Ovine brain 0.210 2.70c & 2.50d 2.3d cLogusch et al. (1989) & dPamiljans et al. (1962)
Canine long form 0.124 1.30 1.90 Shin et al. (2004)
Canine short form 0.067 1.10 1.30 Shin et al. (2004)
Various Plants n.d. ~5 – 10 ~0.3 – 1.3 Acaster et al. (1985)
Pea seed 0.200c n.d. 2.00d cWedler et al. (1976) & dKnight et al. (1988)
Pea leaf 0.161 n.d. n.d. Leason et al. (1982)
Spinach 0.100 n.d. n.d. Lea et al. (1989)
Yeast n.d. 5.40 0.300 (Kim and Rhee 1987) Kim et al. (1987)
S. Typhimurium n.d. 1.10e 0.580f eLiaw et al. (1993) & fLiaw et al. (1994)
E. Coli 0.001g,h 3.00g,h, 5.50i 0.400i gVillafranca et al. (1976), hWedler et al. (1976) & iAlibhai et al. (1994)