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. Author manuscript; available in PMC: 2014 Oct 2.
Published in final edited form as: Nat Mater. 2011 Dec 4;11(1):82–90. doi: 10.1038/nmat3187

Table 2.

Physical properties of polyplex nanoparticles formed from DNA (pGL4.13) and lactone-DES-MDEA terpolymer.

Polymer name* N/P
(molar ratio)
Mean particle
radius (nm)
Zeta potential
(mV)
PMSC 116 70 15.7
I-10%CL 111 73 11.3
I-20%CL 105 107 10.8
I-40%CL 91 45 15.3
I-60%CL 72 43 16.7
I-80%CL 45 117 7.3
II-10%DDL 107 69 10.4
II-20%DDL 99 93 11.6
II-40%DDL 79 90 8.9
III-10%PDL 106 86 13.2
III-20%PDL 96 75 8.9
IV-10%HDL 105 - -
*

See Table 1 for polymer nomenclature.

All polyplex nanoparticles were formed at 100:1 weight ratio (polymer/DNA).

PMSC is included here as a reference polymer.