Table 1. Annual influenza virus strains used in Anflu® (Northern Hemisphere) and clinical trials sponsored by Sinovac.

Season	H1N1	H3N2	B	Study site	Subjects	Objectives	Ref
2002/2003	A/New Caledonia/20/99	A/Moscow/10/99	B/Hong Kong/330 /2001	Liucheng country CDC, Guangxi province	6–35 months, and 6–12, 16–60, >60 years	Safety and immunogenicity	21
2006/2007	A/New Caledonia/20/99	A/California/7/2004	B/Shang Hai/361 /2002	Tianjin city CDC	18–60 and >60 years	Safety	29
				Beijing CDC	18–60 and >60 years	Safety	*
2007/2008	A/Solomon Islands/3/2006	A/Hiroshima/52/2005	B/Malaysia/2506 /2004	Tianjin city CDC	18–60 years	Safety and immunogenicity	22
				Lanshan country CDC, Hunan province	>60 years	Safety and immunogenicity	23
				14 city or country CDCs	6–35 months, and 3–12, 12–17, 18–60, >60 years	Safety	30, 24, 25
2008/2009	A/Brisbane/59/2007	A/Brisbane/10/2007	B/Florida/4/2006	Qingdao city CDC, Shandong province	18–60 and >60 years	Safety and immunogenicity	26
				5 city or country CDCs	6–35 months, and 3–12, 18–60, >60 years	Safety	*
2009/2010	A /Brisbane/ 59/2007	A/ Uruguay/716/2007	B/Brisbane/60/2008	Lingchuan country CDC, Guangxi province	6–35 months	Safety and immunogenicity	27
				Beijing CDC	18–60 years	Safety and immunogenicity	31
2010/2011	A/California/7/2009	A/Victoria/210/2009	B/Brisbane/60/2008	Shenyang city CDC, Liaoning province	18–60 and >60 years	Safety and immunogenicity	28
2011/2012	A/California/7/2009	A/Perth/16/2009	B/Brisbane/60/2008	Zhengding country CDC, Hebei province	6–35 months	Safety	*
2012/2013	A/California/7/2009	A/Victoria/361/2011	B/Hubei-Wujiagang/158/2009	Yuanyang country CDC, Henan province	6–35 months, and 18–60 and >60 years	Safety and immunogenicity	*

^*Unpublished.