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. 2014 Oct 1;8:116. doi: 10.3389/fncir.2014.00116

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Copyright © 2014 Grothe and Pecka.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Both the ILD and ITD code is based on hemispheric tuning functions. The azimuthal tuning function of both LSO and MSO span a wide range of azimuthal space. (A) LSO neurons respond best to ipsilateral sound-source positions (compare Figure 4B). This ipsi-preference is flipped to a contra-preference upstream of the LSO because of the contralateral projections of LSO neurons to the midbrain. (B) MSO neurons respond best to contralateral sound-source positions. This contra-preference is maintained upstream of the LSO because of the ipsilateral projections of MSO neurons to the midbrain.