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Schematic representation of promoter region of IL-6 gene from -600 to +1. Nucleotide sequence shown in text box, the 5’ and 3’ primers for -597A/G SNP are shown in blue while those for -174G/C are shown in red. GATG, FokI recognition site; *, Nla III restriction site; AP-1, activator protein-1; NRD, negative regulatory domain; CRE, cAMP responsive element; GRE, glucocorticoid responsive element; TATA, TATA box; NF-kB, nuclear factor - kB.
