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. 2014 Apr;9(2):181–187.

Table 1.

Allele and genotype frequency of complement H factor variant Y402H and ARMS2 variant A69S in age related macular degeneration (AMD) cases and non-AMD controls

CFH Y402H
Allele Genotype
Frequency P value Frequency P value
Case control Case control
T 59 (42.1%) 106 (61.6%) 0.002 TT 13 (18.6%) 35 (40.7%) 0.005
C 81 (57.9%) 66 (38.4%) TC 33 (47.1%) 36 (41.9%)
CC 24 (34.3%) 15 (17.4%)
LOC387715 A69S
Allele Genotype
Frequency P value Frequency P value
Case control Case control
G 58 (41.4%) 142 (82.6%) 0.002 GG 17 (24.3%) 58 (67.4%) <0.0001
T 82 (58.6%) 30 (17.4%) GT 24 (34.3%) 26 (30.3%)
TT 29 (41.4%) 2 (2.3%)