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. 2014 Oct 1;5:154. doi: 10.3389/fendo.2014.00154

Figure 6.

Figure 6

The “lazy zone” is an artifact associated with background mechanical strain stimuli. Increasing mechanical strain is associated with a linear increase in bone mass in studies when background strains are eliminated in the isolated avian ulna [(A), (91)] and combined sciatic neurectomy and tibial loading models [(B), (86)]. This indicates there is no “lazy zone” in bone’s adaptation to loading [(C), (86)]. MES, minimum effective strain stimulus.