Figure 5. The effects of T-2 toxin on caspase-9 and caspase-3 activities in human chondrocytes.

Cells were treated with 1, 10, 20 ng/ml T-2 toxin and 1 uM Na₂SeO₃+20 ng/ml T-2 toxin for 5 d. The activities of caspase-9 (A) and caspase-3 (B) were measured using the substrate Ac-LEHD-pNA and Ac-DEVD-pNA, separately. *P<0.05 vs. control; #P<0.01 vs. 20 ng/ml T-2 toxin group.