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. Author manuscript; available in PMC: 2014 Oct 2.
Published in final edited form as: Psychol Med. 2009 Nov 9;40(7):1063–1077. doi: 10.1017/S0033291709991723

Table 2.

Notable psychiatric GWAS findings (as of September 2009)

Disease Citation Locus Subjects MAF, OR† Best SNP & P-value
Autism (Wang et al., 2009) CDH10-CDH9 intergenic 12,834 0.38, 1.19 rs4307059, 2×10−10
Bipolar disorder (Ferreira et al., 2008) ANK3
CACNA1C 		10,596
10,596		 0.05, 1.45
0.32, 1.18		 rs10994336, 9×10−9
rs1006737, 7×10−8
Schizophrenia (O’Donovan et al., 2008a, International Schizophrenia Consortium, 2009, Shi et al., 2009, Stefansson et al., 2009) MHC-NOTCH4 region
MHC-histone cluster
NRGN
TCF4
ZNF804A 		47,536
47,536
47,536
47,536
20,142		 0.85, 1.15
0.87, 1.19
0.83, 1.15
0.06, 1.23
0.59, 1.12		 rs3131296, 2×10−10
rs6913660, 1×10−9
rs12807809, 2×10−9
rs9960767, 4×10−9
rs1344706, 2×10−7
†

Illustrative minor allele frequency (MAF) in controls and odds ratio (OR).