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. Author manuscript; available in PMC: 2014 Oct 2.
Published in final edited form as: Thorax. 2012 Apr 27;67(9):769–776. doi: 10.1136/thoraxjnl-2011-200253

Table 2.

Change From Baseline in Asthma Quality of Life (AQOL)

Mean (SE) Mean (95% (CI)
Change from baseline to
Baseline 10 Weeks 6 Months 12 Months 10 Weeks 6 Months 12 Months P Val*
AQOL Overall Score n=82 n=74 n=76 n=80
    MBSR 5.34(0.15) 5.80(0.13) 5.89(0.13) 5.97(0.12) 0.46(0.23,0.69) 0.55(0.34,0.76) 0.64(0.40,0.87) 0.015++
    HLC Control 5.50(0.14) 5.74(0.14) 5.79(0.14) 5.58(0.14) 0.24(0.02,0.47) 0.29(0.09,0.50) 0.09(−0.15,0.33)
Intervention Effect 0.22(−0.10,0.54) 0.26(−0.04,0.55) 0.55(0.21,0.89) †
P Value 0.191 0.092 0.001
Four AQOL
Domains:
Activity Limitations n=82 n=74 n=76 n=80
    MBSR 5.29(0.17) 5.66(0.15) 5.86(0.15) 5.97(0.13) 0.37(0.10,0.65) 0.57(0.29,0.85) 0.68(0.38,0.98) 0.028++
    HLC Control 5.45(0.16) 5.71(0.15) 5.83(0.15) 5.56(0.15) 0.26(−0.01,0.52) 0.38(0.11,0.66) 0.11(−0.19,0.41)
Intervention Effect 0.12(−0.26,0.50) 0.19(−0.20,0.58) 0.57(0.15,1.00)†
P Value 0.581 0.371 0.005
Symptoms n=82 n=73 n=76 n=80
MBSR 5.37(0.15) 5.87(0.14) 5.91(0.14) 5.96(0.13) 0.50(0.25,0.50) 0.54(0.33,0.50) 0.59(0.34,0.84) 0.055++
HLC Control 5.48(0.15) 5.76(0.15) 5.76(0.15) 5.61(0.15) 0.29(0.03,0.54) 0.29(0.08,0.50) 0.14(−0.12,0.39)
Intervention Effect 0.22(−0.14,0.57) 0.25(−0.04,0.55) 0.46(0.10,0.81)†
P Value 0.239 0.093 0.009
Emotional Function n=82 n=74 n=76 n=80
    MBSR 5.54(0.18) 6.03(0.15) 6.09(0.13) 6.27(0.13) 0.50(0.22,0.78) 0.56(0.31,0.81) 0.74(0.44,1.04) 0.019++
    HLC Control 5.63(0.17) 5.96(0.15) 5.90(0.14) 5.74(0.15) 0.33(0.05,0.61) 0.27(0.02,0.52) 0.11(−0.20,0.43)
Intervention Effect 0.17(−0.23,0.56) 0.29(−0.07,0.64) 0.63(0.19,1.07)†
P Value 0.405 0.090 0.002
Environmental
Stimuli 		n=80 n=73 n=76 n=79
    MBSR 5.59(0.17) 5.97(0.15) 5.86(0.15) 5.89(0.15) 0.38(0.11,0.65) 0.27(0.02,0.53) 0.30(0.02,0.38) 0.235++
    HLC Control 5.78(0.17) 5.86(0.16) 5.89(0.15) 5.70(0.16) 0.09(−0.17,0.35) 0.11(−0.14,0.36) −0.08(−0.36,0.20)
Intervention Effect 0.29(−0.08,0.67) 0.16(−0.20,0.52) 0.38(−0.01,0.78)
P Value 0.129 0.400 0.057
*

The p-value results from the likelihood ratio test comparing models with and without the group-time interaction.

++

A cubic transformation was used to meet the distributional assumptions of the model (providing appropriate p-values for testing). Estimates shown in the table were derived from the models and back transformed into the original units for ease of interpretation.

†

The p-value for the group-time interaction at the particular time-point ≤ 0.05.