Table 3.
Change From Baseline in Lung Function
| Mean (SE) | Mean (95% (CI) Change from baseline to |
|||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | 10 Weeks | 6 Months | 12 Months | 10 Weeks | 6 Months | 12 Months | P Val* | |
|
2-week Average AM Peak Flow (PEF) (liters/min) |
n=78 | n=63 | n=63 | n=63 | ||||
| MBSR | 445.5(21.6) | 440.7(22.2) | 443.7(21.5) | 448.5(23.7) | −4.8(−31.5,21.8) | −1.9(−27.1,23.4) | 2.9(−26.5,32.4) | 0.974 |
| HLC Control | 394.5(22.2) | 398.7(22.8) | 400.9(22.1) | 405.7(24.6) | 4.2(−23.2,31.6) | 6.4(−19.7,32.5) | 11.3(−20.1,42.7) | |
| Intervention Effect | −9.0(−47.3,29.2) | −8.2(−44.6,28.1) | −8.3(−51.4,34.7) | |||||
| P Value | 0.644 | 0.656 | 0.705 | |||||
|
Peak Expiratory Flow (PEF) Variability (%) |
n=77 | n=64 | n=63 | n=62 | ||||
| MBSR | 8.86(0.78) | 7.26(0.70) | 9.20(0.76) | 8.17(0.90) | −1.60(−3.10,−0 .10) | 0.34(−1.49,2.17) | −0.69(−2.42,1.04) | 0.032 |
| HLC Control | 9.19(0.79) | 8.46(0.69) | 7.30(0.76) | 8.45(0.95) | −0.73(−2.23,0.77) | −1.89(−3.73,−0.05) | −0.75(−2.57,1.08) | |
| Intervention Effect | −0.87(−2.99,1.26) | 2.23(−0.37,4.83) | 0.06(−2.46,2.57) | |||||
| P Value | 0.424 | 0.092 | 0.966 | |||||
|
Spirometry (FEV1) (liters) |
n=83 | n=66 | n=63 | n=78 | ||||
| MBSR | 2.57(0.10) | 2.61(0.11) | 2.62(0.11) | 2.60(0.11) | 0.04(−0.03,0.11) | 0.05(−0.02,0.13) | 0.03(−0.05,0.11) | 0.408 |
| HLC Control | 2.54(0.10) | 2.65(0.11) | 2.61(0.11) | 2.56(0.11) | 0.11(0.04,0.11) | 0.07(−0.002,0.15) | 0.02(−0.06,0.11) | |
| Intervention Effect | −0.07(−0.18,0.03) | −0.02(−0.13,0.09) | 0.01(−0.11,0.13) | |||||
| P Value | 0.159 | 0.692 | 0.917 | |||||
*
The p-value results from the likelihood ratio test comparing models with and without the group-time interaction.