Fig. 6.

Dopamine administration increases the number of insulin-expressing cells in pancreatic explants. (a) Double immunostaining for insulin (INS, cyan) and glucagon (GCG, red) in explants cultured for 5 days. Nuclei are stained with DAPI. Scale bar, 100 μm. (b, c) Quantification of total number of insulin- and glucagon-expressing cells. Results represent the mean ± SEM of five explants per condition. *p < 0.05 vs control (d) Quantification of the number of BrdU⁺ cells in cytospin of explants cultured for 5 days. Results represent the mean ± SEM of at least four explants per condition. *p < 0.05 vs control