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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Breast Cancer Res Treat. 2014 Sep 19;147(3):661–670. doi: 10.1007/s10549-014-3135-z

Table 2.

All-cause mortality and competing risks of breast cancer (BC)-specific mortality and non-BC-specific mortality associated with neighborhood socioeconomic deprivation and tumor subtypes (TNBC vs. non-TNBC).

Person-Years All-cause Mortality
Competing Risk Model
BC-specific mortality
Non-BC-specific mortality
Cases HR (95% CI) Cases HR (95% CI) Cases HR (95% CI)
Bivariate models
 Neighborhood Socioeconomic Deprivation Quartile
  1st (lowest) 4681 61 1.00 51 1.00 10 1.00
  2nd 4570 65 1.08 (0.76–1.53) 44 0.87 (0.58–1.30) 21 2.14 (1.01–4.56)
  3rd 4476 82 1.37 (0.99–1.92) 52 1.04 (0.70–1.53) 30 3.11 (1.52–6.37)
  4th (highest) 4329 141 2.19 (1.62–2.97) 86 1.58 (1.11–2.24) 55 5.34 (2.71–10.5)
  Ptrenda <0.001 <0.001 <0.001
  Pheterogeneityb - 0.010
 Tumor subtype
  Non-TNBC 15137 218 1.00 143 1.00 75 1.00
  TNBC 2919 131 2.86 (2.30–3.56) 90 3.04 (2.33–3.97) 41 2.52 (1.71–3.70)
  Pheterogeneity - 0.655
Multivariate models
 Neighborhood Socioeconomic Deprivation Quartile
  1st (lowest) 4681 61 1.00 51 1.00 10 1.00
  2nd 4570 65 0.97 (0.67–1.41) 44 0.84 (0.55–1.28) 21 1.70 (0.79–3.68)
  3rd 4476 82 1.12 (0.78–1.60) 52 0.88 (0.58–1.34) 30 2.48 (1.18–5.18)
  4th (highest) 4329 141 1.41 (0.94–2.13) 86 1.15 (0.71–1.87) 55 2.98 (1.33–6.66)
  Ptrend 0.055 0.300 0.023
  Pheterogeneity - 0.007
 Tumor subtype
  Non-TNBC 15137 218 1.00 143 1.00 75 1.00
  TNBC 2919 131 1.56 (1.15–2.12) 90 1.42 (0.99–2.03) 41 2.15 (1.20–3.84)
  Pheterogeneity - 0.655

Multivariate models were controlled for age, race, marital status, health insurance coverage, tumor stage, tumor grade, comorbidity, hormone therapy, trastuzumab therapy, chemotherapy, radiotherapy, type of surgery, alcohol use, and smoking status;

a

P value of trend test indicates if there is a significant trend in the effect of neighborhood socioeconomic deprivation;

b

P value of heterogeneity test indicates if there is a difference in the effects of neighborhood socioeconomic deprivation and TNBC subtype on BC-specific vs. non-BC-specific mortality in the competing-risk models.