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. Author manuscript; available in PMC: 2014 Oct 2.
Published in final edited form as: J Pharmacogenomics Pharmacoproteomics. 2014 Jan 25;5(1):T-001. doi: 10.4172/2153-0645.T-001

Table 4.

Summary of Attributes for Equation 1 of the Pharmacogenetic Warfarin Dosing Initiation Prediction in Puerto Ricans using the Derivation Cohort from the VACHS.

Variablesa Partial regression coefficient SE R2 after entry p-value
Age −0.0106 0.003 0.0564 0.003
BSA 0.131 0.158 0.0658 0.406
CYP2C9 −0.192 0.048 0.1421 0.000
VKORC1AA −0.227 0.067 0.1538 0.001
VKORC1 GA −0.635 0.092 0.4088 0.000
Admixture Index 2 −0.0780 0.082 0.4210 0.345
3 −0.116 0.088 0.192
4 −0.124 0.079 0.119
Target INR 0.215 0.126 0.4317 0.093
Statins −0.0491 0.060 0.4398 0.415
Amiodarone −0.237 0.171 0.4514 0.168
Smoke −0.118 0.130 0.4568 0.368
Diabetes 0.137 0.066 0.4741 0.040
Vitamin K 0.0943 0.090 0.4809 0.297

Constant value of the model equation is 2.189 (SE: 0.457).

a

Variables are listed in the order they were incorporated into the model using stepwise regression analysis.