Table 2.
Single-SNP association results for CYP17 gene polymorphisms with body mass index (BMI) and fat mass.
| No. | SNP ID | Physical positiona | Allelesb | MAF | Location | BMI P value | Fat mass P value |
|---|---|---|---|---|---|---|---|
| 1 | rs11191416 | 104594906 | A/C | 0.094 | Promoter | 0.320 | 0.237 |
| 2 | rs6163 | 104586914 | C/A | 0.397 | Exon1 | 0.018 | 0.079 |
| 3 | rs3740397 | 104582665 | C/G | 0.396 | Intron5 | 0.016 | 0.083 |
| 4 | rs10883783 | 104581142 | T/A | 0.301 | Intron7 | 0.064 | 0.299 |
| 5 | rs4919685 | 104577352 | C/A | 0.301 | 3′ UTR | 0.064 | 0.299 |
| 6 | rs4919682 | 104574320 | G/A | 0.287 | 3′ UTR | 0.080 | 0.310 |
| 7 | rs619824 | 104571278 | C/A | 0.442 | 3′ UTR | 0.039 | 0.058 |
a
Positions are based on the NCBI web site (http://www.ncbi.nlm.nih.gov/SNP/).
b
The second allele is the minor allele. MAF = minor allele frequency. Results with P values <0.05 are shown in bold.