Table III.

Neonatal neurologic complications and distribution of IVH lesions by severity level

	Cocaine exposed		Nonexposed		χ2/Zc	P
	n	%	n	%
Complication
Seizures*	1	2	2	5	0.4	NS
Periventricular leukomalacia*	2	6	2	6	0.2	NS
Intraventricular hemorrhage	22	54	12	29	2.1	<0.02
(IVH-group mean grade)†	(1.1 ± 1.2)		(0.6 ± 1.2)		1.7	<0.05
IVH category (severity)
No IVH	19	46	29	71
Grades I–II	17	42	8	20
Grades III–IV	5	12	4	9

Overall χ² = 5.4, p <0.07; χ² (0 – grades I–II × cocaine status) = 5.3, p <0.02.

Zc, Statistical test of proportions with the continuity correction; NS, not significant.

^*Based on the Fisher Exact Test.

^†Mean ± SD.