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. Author manuscript; available in PMC: 2014 Oct 2.
Published in final edited form as: Toxicol Appl Pharmacol. 2012 Sep 27;265(1):19–26. doi: 10.1016/j.taap.2012.09.019

Fig. 5.

Fig. 5

B, Atrazine selectively inhibits PDE4 in pituitary cells. A and B, Concentration dependence of atrazine on cAMP release in the presence of BRL-50481, a PDE7 inhibitor (B), but not in the presence of rolipram, a PDE4 inhibitor (A). Data are shown as the mean ± SEM from six replicates in one of three similar experiments. C, Time course of rolipram and atrazine-induced cAMP release. Notice the lack of effects of atrazine on cAMP release in the presence of rolipram and of BRL-50481 alone. Data are shown as the mean ± SEM from six replicates in one of three similar experiments. * p<0.01 vs. control.