Table 3.

Noncompartmental analysis of analgesic formulations

	Tmax (h)	Cmax (ng/mL)	t1/2 (h)	AUClast	Tlast (h)	AUCinf (hr*ng/mL)	Cl/Fpred
Bup-SR	4	14.5 ng/mL	10.1	322 h×ng/mL	72	325 h×ng/mL	1.85 L/h/kg
Butp-SR	2	390 ng/mL	not done	910 h×ng/mL	24	not done	not done
Fent-SR	2	62.1 ng/mL	6.28	279 h×ng/mL	24	288 h×ng/mL	12.2 L/h/kg
Melox-SR	2	7370 ng/mL	6.96	44,200 h×ng/mL	72	44,300 h×ng/mL	0.136 L/h/kg
Melox	2	4740 ng/mL	3.08	12,500 h×ng/mL	12	12,900 h×ng/mL	0.077 L/h/kg
Carp-SR	4	149 µg/mL	10.2	1130 h×µg/mL	72	1140 h×µg/mL	13.2 mL/h/kg
Carp	2	52.5 µg/mL	6.88	399 h×µg/mL	24	434 h×µg/mL	11.5 mL/h/kg

T_max, time of C_max; C_max, maximal concentration measured ; t_1/2, terminal half-life; AUC_last, AUC from time 0 to T_last; T_last, time point at which AUC_last was calculated; AUC_inf, AUC to infinity; Cl/F_pred, predicted clearance.