Table I.

Hemodynamic Data

	Sham		MI		TAC

	Placebo (N=10)	E2 (N=8)	Placebo (N=21)	E2 (N=21)	Placebo (N=20)	E2 (N=18)
Infarct Size (%)			28.4±1.5	31.3±1.6
HR (bpm)	529±14	530±19	507±11	564±6^*	554±10	580±6^†
LVSP (mmHg)	94.6±2.2	95.0±3.1	89.0±1.4	84.9±2.1^†	149±2^‡	144±3^‡
Gradient (mmHg)	4.4±2.1	4.0±4.0	-	-	64.2±3.1^†	55.1±6.5^†
LVEDP (mmHg)	3.1±1.0	2.7±1.4	7.3±0.8^†	9.3±1.3^†	11.8±1.4^†	12.4±1.5^†
+dP/dt (mmHg s⁻¹)	10452±535	9575±315	8378±211^†	6734±289^†^*	8836±190^†	8467±213^†

All data are means±sem. HR=heart rate, LVSP=LV systolic pressure; Gradient refers to systolic pressure drop across the aortic stricture in TAC animals. LVEDP=LV end diastolic pressure; +dP/dt=peak positive dP/dt derived from the first differential of the LV pressure tracing.

p<0.05 vs. Placebo-MI,

^†

p<0.05 vs. the respective sham group.

^‡

p<0.01 vs. the respective sham and MI group.