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. 2014 Sep 23;9:4507–4520. doi: 10.2147/IJN.S68526

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© 2014 Lozano-Pérez et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Effects of unloaded FNPs, resveratrol, RL-FNPs, and dexamethasone on colonic gene expression, in TNBS rat colitis, of the cytokines (A) IL-1β, (B) IL-6, (C) TNF-α, and (D) IL-12, analyzed by real-time PCR.

Notes: PCR data are expressed as mean ± SEM (n=10). Groups with a different letter (a–d) differ statistically (P<0.05).

Abbreviations: Dex, dexamethasone; FNP, silk fibroin nanoparticle; IL, interleukin; PCR, polymerase chain reaction; Resv, resveratrol; RL-FNP, resveratrol-loaded silk fibroin nanoparticle; SEM, standard error of the mean; TNBS, trinitrobenzene sulphonic acid; TNF, tumor necrosis factor.