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. 2014 May 7;8(4):436–442. doi: 10.1111/irv.12255

Table 3.

Predictors of severity as measured by a composite endpoint of admission to the intensive care unit, hospitalization >5 days, oxygen requirements, or death

Univariable analysis Multivariable analysis


OR 95% CI P value OR 95% CI P value
HRV/ENT versus RSV 2·9 1·7, 5·1 <0·001 1·7 0·9, 3·2 0·082
HRV/ENT versus FLU 3·6 2·0, 6·4 <0·001 3·0 1·6, 5·6 0·001
HRV/ENT versus others 2·6 1·4, 4·9 0·003 1·8 0·9, 3·6 0·094
Age 1·1 1·0, 1·1 0·005 1·0 1·0, 1·1 0·180
Cardio-respiratory 2·7 1·6, 4·6 <0·001 2·2 1·2, 4·0 0·007
Prematurity 1·2 0·6, 2·6 0·657
Immunocompromised Metabolic 5·3 3·2, 8·7 <0·001 4·7 2·8, 8·0 <0·001

HRV/ENT, enterovirus/rhinovirus; RSV, respiratory syncytial virus; FLU, influenza; others: PIV, parainfluenza; hMPV, human meta-pneumovirus; ADV, adenovirus, coronaviruses, HBoV.

Values indicated in bold were considered as significant P < 0.05.