Table 2.
Year-wise samples showing amino acid changes in different domains of NS1 gene.
| Domain | Position | Prevalence of mutation in samples each year | ||||
|---|---|---|---|---|---|---|
| 2009 (18) | 2010 (21) | 2011 (17) | 2012 (22) | 2013 (13) |
||
| RNA binding domain | I 43 N | 1 | — | — | — | — |
| D 53 N | 2 | — | — | — | — | |
| E 55 Q | 3 | 16 | 6 | — | 1 | |
| E 55 K | — | — | — | — | 1 | |
| K 62 R | — | 1 | 1 | — | — | |
| S 73 T | — | 1 | 3 | — | — | |
|
| ||||||
| Effector domain | L 90 I | — | — | 8 | all | all |
| T 94 A | 2 | — | — | — | — | |
| E 96 K | — | 2 | — | — | — | |
| R 108 K | 4 | — | — | — | — | |
| I 123 V | 16 | 20 | all | all | all | |
| V 129 A | 1 | — | 1 | — | — | |
| V 129 I | — | — | 6 | — | — | |
| K 131 E | — | — | — | — | 4 | |
| K 131 Q | — | — | — | 2 | — | |
| I 145 L | — | 1 | — | — | — | |
| I 145 V | — | 5 | 1 | — | — | |
| L 147 R | — | — | 1 | — | — | |
| T 151 P | — | 1 | — | — | — | |
| E 172 K | 2 | — | — | — | — | |
| A 202 P | — | — | — | — | 1 | |
| N 205 S | — | — | 13 | all | all | |
| N 209 D | 2 | 1 | — | — | — | |