Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jun 25;122(10):1015–1027. doi: 10.1289/ehp.1307177

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, “Reproduced with permission from Environmental Health Perspectives”); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.

PMC Copyright notice

Meta-analysis results from a two-step mixed-effects model using combined relevant mouse studies in which dams were treated with PFOA via gavage and progeny weight was measured at or soon after birth. Data are presented as the mean (95% CI) change in body weight (g) per 1-unit increase in dose (mg/kg BW/day). Each box represents the dose–response slope estimate for a study; the midpoint of the box is the slope estimated for that study, and the box area is proportional to the weight given to each study in the meta-analysis. The diamond is centered at the overall meta-analysis slope estimate. Wolf (2007) was split into two data sets: a) cross-foster (exposure on GDs 1–17), and b) windows of sensitivity (exposure groups for GDs 7–17, GDs 10–17, GDs 13–17, and GDs 15–17).