Table 3.
Unadjusted and adjusted regression coefficients (for FT4, ln-transformed TSH, and ln-transformed TPOAb) and odds ratios (for TPOAb ≥ 10 IU/mL vs. < 10 IU/mL) for associations with ln-transformed mid-pregnancy blood lead concentrations, Pristina and Mitrovica combined.
| Outcome | Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|---|
| R2 (n) | β or OR (95% CI) | p-Value | R2 (n) | β or OR (95% CI)a | p-Value | |
| FT4 (ng/dL) | 0.11 (279) | –0.079 (–0.11, –0.052) | < 0.0001 | 0.25 (277) | –0.074 (–0.10, –0.046) | < 0.0001 |
| ln-TSH (μIU/mL) | 0.00027 (278) | –0.012 (–0.098, 0.074) | 0.79 | 0.046 (276) | 0.026 (–0.065, 0.12) | 0.58 |
| ln-TPOAb (IU/mL) | 0.075 (291) | 0.34 (0.20, 0.48) | < 0.0001 | 0.094 (291) | 0.31 (0.17, 0.46) | < 0.0001 |
| TPOAb ≥ vs. < 10 IU/mL | 0.062 (291) | 2.51 (1.62, 3.89) | < 0.0001 | 0.074 (291) | 2.41 (1.53, 3.82) | 0.0002 |
| aModel covariates: FT4: height, ethnicity, BMI, fetal gestational age, maternal education, adults per room; TSH: hemoglobin, ethnicity, BMI, fetal gestational age, maternal age; TPOAb (continuous and dichotomous): ethnicity, fetal gestational age, maternal age, adults per room. | ||||||