Table 1.
Characteristic | Participants | ||
---|---|---|---|
All | Diabetica | Nondiabetic | |
All participants | 374 (100) | 66 (17.6) | 308 (82.4) |
Females | 252 (67.4) | 44 (17.5) | 208 (82.5) |
Males | 122 (32.6) | 22 (18.0) | 100 (82.0) |
Age (years) | 49.2 ± 15.6 | 56 ± 12.0* | 48 ± 16.0* |
As in drinking water (ppb) | 55.2 ± 52.8 | 60.0 ± 50.9 | 54.1 ± 53.2 |
BMI | 29.2 ± 6.1 | 30.8 ± 5.4* | 28.9 ± 6.2* |
26 ≤ BMI < 30 | 108 (29) | 19 (29) | 79 (26) |
BMI ≥ 30 | 155 (41) | 31 (47) | 124 (40) |
FPG (mg/dL) | 95.9 ± 39.5 | 155.7 ± 62.8* | 83.2 ± 12.1* |
2HPG (mg/dL) | 118.6 ± 60.4 | 204.9 ± 86.0* | 100.4 ± 31.1* |
FPG ≥ 126 mg/dL | 38 (10.2) | 38 (57.6) | 0 (0) |
2HPG ≥ 200 mg/dL | 33 (8.8) | 33 (50.0) | 0 (0) |
Self-reported diabetes diagnosis | 43 (11.5) | 43 (65.2) | 0 (0) |
Self-reported diabetes medication | 30 (8.0) | 30 (45.5) | 0 (0) |
EUC count in 100 mL urineb | 374,008 ± 726,387 | 352,165 ± 468,388 | 378,689 ± 771,036 |
Sum of As speciesc in EUC (pg As/10,000 cells) | 127.7 ± 359.6 | 90.3 ± 202.1 | 135.7 ± 384.8 |
Sum of As species in urine (ng As/mL) | 73.9 ± 73.2 | 82.0 ± 74.9 | 72.1 ± 72.9 |
Creatinine concentration in urine (mg/dL) | 129.2 ± 90.2 | 127.1 ± 85.7 | 129.6 ± 91.3 |
Sum of As species in urine normalized for creatinine (ng As/mg creatinine) | 65.7 ± 66.5 | 73.1 ± 77.9 | 64.2 ± 63.8 |
Specific gravity of urine | 1.014 ± 0.007 | 1.017 ± 0.008* | 1.014 ± 0.007* |
Sum of As species in urine normalized for specific gravity (ng As/specific gravity unit) | 109.7 ± 101.8 | 92.6 ± 62 | 113.4 ± 108.2 |
aDiabetic individuals were classified by either FPG ≥ 126 mg/dL, 2HPG ≥ 200 mg/dL, self-report of doctor diagnosis, or use of medication for treatment of diabetes. bNeither red nor white blood cells were included in the cell counts. cSum of As species = iAsV + iAsIII + MAsV + MAsIII + DMAsV + DMAsIII. *p < 0.05, for continuous variables, comparing participants with and without diabetes by Student’s t-test. |