Table 1.

Subject demographics

		Placebo n = 8	0.25 mg/kg n = 5	0.50 mg/kg n = 5	0.75 mg/kg n = 5	1.00 mg/kg n = 5	1.25 mg/kg n = 5	1.50 mg/kg n = 5	1.75 mg/kg n = 5	2.00 mg/kg n = 5
Number		8	5	5	5	5	5	5	5	5
Age, years	Mean ± SD	69.0 ± 7.3	67.0 ± 8.8	65.2 ± 13.2	63.4 ± 8.1	55.0 ± 5.2	65.4 ± 8.3	65.8 ± 10.8	64.0 ± 6.4	67.4 ± 7.5
Age	Min–max	61–82	54–78	46–77	58–76	49–61	59–75	51–79	57–72	56–75
Ethnicity / race	Hispanic	0	0	0		0		0	0	0
	White	7 (87.5)	4 (80.0)	4 (80.0)	4 (80.0)	3 (60.0)	4 (80.0)	3 (60.0)	5 (100.0)	3 (60.0)
	African	1 (12.5)	1 (20.0)	1 (20.0)	1 (20.0)	2 (40.0)	1 (20.0)	2 (40.0)	0 (0.0)	2 (40.0)
	American
Sex	Male	6 (75.0)	5 (100.0)	3 (60.0)	5 (100.0)	3 (60.0)	3 (60.0)	4 (80.0)	3 (60.0)	3 (60.0)
	Female	2 (25.0)	0 (0.0)	2 (40.0)	0 (0.0)	2 (40.0)	2 (40.0)	1 (20.0)	2 (40.0)	2 (40.0)
Smoking status	None	0 (0.0)	1 (20.0)	0 (0.0)	1 (20.0)	1 (20.0)	0 (0.0)	0 (0.0)	0 (0.0)	1 (20.0)
	Former	3 (37.5)	2 (40.0)	4 (80.0)	0 (0.0)	1 (20.0)	3 (60.0)	3 (60.0)	2 (40.0)	2 (40.0)
	Current	5 (62.5)	2 (40.0)	1 (20.0)	4 (80.0)	3 (60.0)	2 (40.0)	2 (40.0)	3 (60.0)	2 (40.0)
ABI	Mean ± SD	0.65 ±0.14	0.80 ± 0.24	0.68 ± 0.32	0.57 ±0.17	0.67 ± 0.09	0.65 ±0.15	0.53 ±0.13	0.79 ± 0.08	0.55 ±0.17

ABI, ankle–brachial index.