Table 1. Information of the studies included in the meta-analysis.
Tumor | Control | |||||||
Author | Year | Country | Ethnicity | Method | Age (y) | M+/N | M+/N | Source of Controls |
Sun et al. [21] | 2012 | China | Asian | MSP | 39.3(18–65) | 11/14 | 157/336 | NT |
Niyazi et al. [19] | 2012 | China | Asian | MSP | 41.4(27–62) | 19/30 | 1/30 | BCT |
Missaoui et al. [18] | 2011 | Tunisia | African | MSP | NA | 10/14 | 0/8 | BCT |
Kim et al. [16] | 2010 | Korea | Asian | MSP | NA | 50/69 | 11/41 | BCT |
Yang et al. [22] | 2010 | NE | Caucasian | QMSP | 47(38–57) | 18/60 | 5/20 | BCT |
Iliopoulos et al. [13] | 2009 | Greece | Caucasian | QMSP | 41(18–62) | 41/61 | 0/15 | NT |
Flatley et al. [3] | 2009 | UK | Caucasian | MSP | 34.3(20–84) | 17/42 | 0/40 | NT |
Zhao et al. [23] | 2008 | China | Asian | MSP | 42(25–71) | 34/52 | 0/20 | BCT |
Leung et al. [17] | 2008 | China | Asian | MSP | 52.5(23–85) | 60/107 | 0/27 | AT |
Feng et al. [12] | 2007 | USA | Caucasian | QMSP | 46.8 | 31/63 | 1/16 | NT |
Shivapurkar et al. [20] | 2007 | USA | Caucasian | QMSP | NA | 24/45 | 0/12 | BCT |
Jeong et al. [14] | 2006 | Korea | Asian | MSP | 48.9(24–79) | 35/78 | 1/24 | BCT |
Kang et al. [15] | 2005 | Korea | Asian | MSP | NA | 60/82 | 0/17 | BCT |
Reesink-Peters et al. [24] | 2004 | NE | Caucasian | QMSP | NA | 35/48 | 2/41 | NT |
Dong et al. [11] | 2001 | Korea | Asian | MSP | NA | 27/53 | 0/24 | BCT |
Note: NE: Netherlands; UK: United Kingdom; MSP: methylation-specific polymerase chain reaction; QMSP: real-time quantitative methylation-specific polymerase chain reaction; NA: not applicable; M+: the number of methylations; N: number of total; NT: normal cervical tissues from healthy people; BCT: normal cervical tissues from patients who had benign gynecological diseases such as uterine myoma, adenomyoma, and uterine prolapse; AT: normal cervical tissues adjacent to the tumor.