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Biological activity of hypothiocyanite on bacteria and possible defense mechanism of the bacteria. Reversible inhibition is observed in that (i) hypothiocyanite is not reactive against all thiols and (ii) if hypothiocyanite is removed or diluted, the pathogen recovers. Irreversible inhibition is linked to (i) long period of incubation, (ii) the bacterial species, and (iii) hypothiocyanite concentration. HOSCN/OSCN−: acidic or basic form of hypothiocyanite and GSH: glutathione.
