ROCK1, ROCK2 and/or pMYPT1 are overexpressed in human metastatic lung cancers. Patient matched paired normal (N) and tumorous (T) lung tissues were obtained and the expression patterns of the indicated proteins were determined by Western blot analysis. Roman numerals indicate patient samples as follows: I, squamous cell carcinoma; II, metastatic carcinoma of breast origin; III, metastatic sarcoma; IV, metastatic adenocarcinoma of endometrial origin; V, carcinoma; VI, metastatic pleomorphic sarcoma; VII, squamous cell carcinoma.