Fig. 1.

Alcohol and LPS-induced lung injury model. Radiographic determination of the rate of lung fluid clearance in mice chronically ingesting alcohol [ethanol (EtOH); n = 11] vs. age-matched caloric control animals (CTRL; n = 9) following overnight (o/n) exposure to LPS. The lungs of alcohol-fed animals +LPS stayed flooded, whereas control animals + LPS maintained balance between secretion and absorption after prolonged LPS exposure. *P < 0.01. I-Io, lung fluid clearance measured as X-ray intensity − intensity at time 0.